Stem cells are the precursor cells with the capacity to distinguish into diverse categoriesof cells. They may be determined in several tissues and might have healing implications. Bygone many years have witnessed huge studies on this discipline; as a result, stem cell therapy is now used as a therapeutic modality in lots of conditions and has observed its place in dermatology too. 

Their source of origin and differentiating capacity makes the foundation for their categorization. In skin, they may be determined withinside the interfollicular epidermis, hair follicle, epidermis and adipose tissue. They hold everyday skin homeostasis and assist to restore and regenerate if injured. These particular properties have precipitated their use in the treatment of numerous dermatoses like systemic sclerosis, systemic lupus erythematosus, scleromyxedema, alopecia, Merkel cell carcinoma, pemphigus vulgaris, psoriasis, wound healing and epidermolysis bullosa. They have even been used in esthetic medicine, with inconsistent success. 

The starting of stem cell therapy has brought about the curative treatment of conditions which have been formerly taken into consideration asuntreatable. However, problems like ideal patient selection, the timing of intervention, suitable conditioning regimens, post-intervention care and cost-effectiveness require additional studies to help in optimizing the outcomes of this remedy.